Forskolin is a compound found in Coleus forskohlii, a tropical plant within the mint family. The plant is native to India, and grows wild in numerous countries in Southeast Asia. It’s been used since ancient times to treat asthma, bronchitis, constipation, heart disease along with other conditions. However, it became far more well known in 2014 after Dr. Oz praised it as a “miracle” weight reduction pill.
Forskolin comes being an over-the-counter supplement usually containing 10-20% forskolin extract (often called pure forskolin). Manufacturers state that it suppresses appetite and helps with weight loss. Summary: Forskolin is a compound located in the tropical plant Coleus forskohlii, part of the mint family. It’s been used since olden days to take care of various ailments, and is now marketed and sold as a diet pill.
How Is Forskolin Expected to Work? Forskolin has become studied being a potential weight loss supplement because of the way it affects fat cells. In laboratory studies, forskolin causes fat cells to produce more cAMP (cyclic Adenosine Monophosphate), a chemical messenger that results in the breakdown of fat tissue. Since forskolin causes the breakdown of fat cells in a lab, it’s believed to perform the same in humans. That also remains unproven, however. Summary: Lab studies show that forskolin causes breakdown of fat tissue. It’s still unknown whether or not it has got the same effect in the human body.
Does Forskolin Cause Weight Reduction? Does Forskolin Cause Weight Reduction?Even when forskolin does cause fat tissue to breakdown, that doesn’t necessarily mean it will result in weight-loss. Only two small research has considered whether forskolin causes weight loss in humans. In a clinical trial of 15 obese men, one group was given 500 mg of 10% forskolin extract on a daily basis. After 12 weeks, the body fat percentages from the men taking forskolin decreased significantly – from an average of 35% to 31% – when compared with those given a placebo. Simultaneously, lean body weight in males taking forskolin increased by about 5%. However, while fat mass declined and lean body mass increased, total bodyweight failed to change.
Interestingly, the group taking forskolin also saw their testosterone levels increase, which may cause decreases in unwanted fat. Scientific study has not examined how or if forskolin might cause testosterone levels to increase though. The other study found no influence on weight or unwanted fat in 19 overweight women using the same dosage of forskolin.
Summary: Hardly any studies have been done on forskolin and weight-loss. One small study thought it was decreased excess fat and increased lean body weight in men, however with no overall weight change. Another study on women found no influence on weight or body composition.
Does Forskolin Prevent Excess Weight? Does Forskolin Prevent Putting On Weight?Despite the fact that forskolin does not manage to cause weight-loss, it could prevent putting on weight. Within the second study cited above, overweight women who took forskolin gained less weight over the course of 12 weeks as opposed to those given a placebo. However, the differences were small. The normal weight of women taking forskolin stayed about the same, whilst the average weight from the control group increased slightly (1.3 kg). The ladies did not report any alternation in appetite. A report in rats also suggested that forskolin may prevent putting on weight.
Researchers purposefully overfed rats therefore they would gain weight. The rats were split into two groups – one received forskolin extract throughout the overfeeding period, one other did not. People who received forskolin gained significantly less weight compared to other group – about 75% less. Furthermore, they ate less food along with their cholesterol levels improved significantly. While those two research has revealed promising results, much more research is necessary to determine if forskolin extract can prevent putting on weight in humans. Summary: Two small reports have found that forskolin can help prevent excess weight. A lot more research is necessary to confirm this influence on humans.
Both studies of forskolin and weight in humans failed to find any negative health consequences. Cholesterol, insulin and blood pressure levels were not affected, and no significant negative effects were reported. In those studies, 100-250 ml of the 10% forskolin extract was used twice daily for 12 weeks. The effects of employing a greater dosage or using it for a longer time are unknown.
One half of the nearly 1,300 reviews are 5 stars. Some people claimed to have achieved significant weight reduction, even within the first one to two weeks of taking. Other positive effects reported include: normalized bowel motions, decreased msvkiq and increased energy. Many reported weight-loss alongside diet or exercise (not just from your pill itself).
Many people saw no improvement in weight or general health. Others experienced side effects like diarrhea, bloating, gas, and constipation. A couple of noted its contraindication with their blood pressure levels medication.